Semantic Barriers â€“ These involve the wrong usage of words and symbols, preventing the message from being properly encoded and decoded. Faulty translations and different interpretations lead to wrong impressions in the mind of the sender and receiver.
Psychological Barriers â€“ The senderâ€™s and receiverâ€™s state of mind affects the communication process. The absence of psychological and emotional bonding between the sender and receiver can lead to sending and interpreting of wrong messages.
Organizational Barriers â€“ The structure of an organization and the norms governing them can deter the smooth flow of a communication process. For example, lack of free communication is a hurdle in a centralized organizational pattern.
Personal Barriers â€“ The interpersonal relationship between the sender and receiver can affect the communication process. If the superiors are not confident about the subordinatesâ€™ competence, the latter may not participate in decision-making. Subordinates will also not contribute towards offering useful suggestions if they are not rewarded properly.
Transport across the membrane is accompanied by the reversible change in conformation which results in alternate exposure of the transport molecule binding site on of the carrier protein towards both the faces of the membrane alternatively. Binding occurs at one face, followed by changed conformation which results in the exposure of the binding face of the carrier protein towards the other face of the membrane where the molecule is released. On the release of the substrate molecule, the carrier protein reverts backs to its original conformation and place and exposes its free binding site again. The rate of carrier-mediated transport is maximum when all the binding sites of the protein are bound to a substrate molecule that is to be transported. Small ions, macromolecules, and some small-sized molecules act as the substrates for these proteins. Glucose transporters, urea transporters, ion transporters are examples of carrier molecules.
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